ROS1 gene 5’ end labeled as orange, with a length of 220 kb; ROS1 gene 3’ end labeled as green, with a length of 600 kb.
Overview
ROS1 gene probe is used to detect rearrangements of the ROS1 at 6q22.1), and is a standard clinical requirement for patients with non-small cell lung cancer (NSCLC) to identify those who may benefit from ROS1-targeted tyrosine kinase inhibitors (TKIs) like Crizotinib or Entrectinib.