IGK gene 5’ end labeled as green, with a total length of 590 kb; IGK gene 3’ end labeled as orange, with a length of 245 kb.
Overview
Kappa chain probe is used to evaluate the expression or genomic arrangement of the immunoglobulin kappa (IGK) light chain, essential in hematopathology to determine clonality—whether a population of B-cells is reactive (normal) or neoplastic (cancerous).