D7S486 locus (7q31) labeled as orange, with a length of 335 kb; 7 chromosome centromere (CEP7) labeled as green.
Overview
D7S486/CEP7 probe is used to identify abnormalities in chromosome 7 within patients suspected of having Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML). It is designed to distinguish between a complete loss of the chromosome (Monosomy 7) and a partial deletion of the long arm (7q-).