IGL gene 5’ end labeled as orange, with a length of 400 kb; IGL gene 3’ end labeled as green, with a length of 1110 kb.
Overview
Lambda chain probe is used to evaluate the expression or genomic arrangement of the immunoglobulin lambda (IGL) light chain, essential for determining clonality in B-cell populations, helping to distinguish between benign reactive processes and malignant lymphoproliferative disorders.