BRAF gene 3’ end labeled as green, with a length of 200 kb; BRAF gene 5’ end labeled as orange, with a length of 200 kb.
Overview
BRAF (7q34) gene break-apart probe is used to detect rearrangements, such as translocations or inversions, involving the BRAF gene. While BRAF is most famous for point mutations (like V600E), its rearrangements are critical drivers in specific pediatric brain tumors and other rare malignancies.