KMT2A (MLL) gene 5’ end labeled as green, with a length of 440 kb; KMT2A (MLL) gene 3’ end labeled as orange, with a length of 290 kb.
Overview
KMT2A(MLL) break apart probe is used to detect chromosomal rearrangements (translocations) involving the KMT2A gene at chromosome 11q23.3, as it is critical in diagnosing acute leukemia’s, especially in infants, where rearrangements occur in 70–80% of cases.