Product
ETV6 (TEL)/RUNX1 (AML1) gene translocation probe reagent
Product summary
- Chromosome
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- 12
- 21
- Label
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- Product code
- FP-029(100µL/kit)
- Regulatory status
- RUO
- Disease
- Acute Lymphoblastic Leukemia (ALL)
ETV6(TEL) gene labeled as orange, with a total length of 600 kb; AML1(RUNX1) labeled as green, with a total length of 1100 kb.
Overview
ETV6 (TEL)/RUNX1 (AML1) translocation probe is used to detect the t(12;21)(p13.2;q22.1) fusion, which is often invisible on a standard karyotype. This probe is critical in diagnosing and determining the prognosis of pediatric B-cell Acute Lymphoblastic Leukemia (B-ALL), where this translocation occurs in roughly 25% of cases.
Product documentation
RUO Instructions for Use
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RUO Instructions for Use