P16 gene (9p21.3) labeled as orange, with a length of 300 kb; 9 chromosome centromere (CEP9) labeled as green.
Overview
P16 gene deletion probe (often termed a CDKN2A deletion probe) is used to detect the loss of the CDKN2A tumor suppressor gene located at chromosome 9p21.3. This deletion is a hallmark of various cancers, including Acute Lymphoblastic Leukemia (ALL), malignant mesothelioma, and high-grade gliomas