CCND1 (BCL1) gene 5’ end labeled as green, with a length of 610 kb; CCND1 (BCL1) gene 3’ end labeled as orange, with a length of 580 kb.
Overview
CCND1 (BCL1) break apart probe used to detect rearrangements (translocations) involving the CCND1 gene on chromosome 11q13.3 and is a primary tool for diagnosing Mantle Cell Lymphoma (MCL), as over 95% of MCL cases harbor the t(11;13)(q13;q32) translocation.