RARA gene 5’ end labeled as orange, with a length of 160 kb; RARA gene 3’ end labeled as green, with a length of 160 kb.
Overview
RARA gene break apart probe is used to detect rearrangements of the RARA (Retinoic Acid Receptor Alpha) gene at chromosome 17q21.2. This probe is primarily used to identify Acute Promyelocytic Leukemia (APL) cases that involve variant translocations with partner genes other than the standard PML