MET gene (7q31.2) labeled as orange, with a length of 390 kb; 7 chromosome centromere (CEP7) labeled as green.
Overview
MET gene probe is used to detect copy number variations, specifically amplifications, of the MET proto-oncogene located on chromosome 7q31.2 and is a key diagnostic tool in non-small cell lung cancer (NSCLC) and gastric cancer to identify patients who may benefit from MET-targeted therapies like Capmatinib or Crizotinib.