IVD - FP021 RB1 Gene Deletion Probe Detection Kit

Cat.# FP-021: RB1 Gene Deletion Probe Detection Kit

[Overview] 

RB1 (RB Transcriptional Corepressor 1) protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008].

[Download] RB1 Gene Deletion Probe Instructions

[Download MSDS] MSDS