RUO - FP231 NTRK2(9q21) Gene Amplification Probe Detection Kit
Cat.# FP-231-2: NTRK2(9q21) Gene Break Apart Probe Detection Kit (RUO)
[Overview]
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
