IVD - FP160 IRF4(6p25) Gene Break Apart Probe Detection Kit

Cat.# FP-160: IRF4(6p25) Gene Break Apart Probe Detection Kit (IVD)

 

[Overview] 

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010].

                     

[Download] IRF4(6p25) Gene Break Apart Probe Instructions

[Download MSDS] MSDS