IVD - FP151 MYEOV/IGH Gene Fusion Probe Detection Kit

Cat.# FP-151: MYEOV/IGH Gene Fusion Probe Detection Kit

[Overview]

MYEOV is a putative oncogene, located centromeric to CCND1, which is thought to be activated in the translocation by becoming closely associated with IGH enhancers. In contrast to IGH rearrangements in other neoplasms, those found in MM have IGH breakpoints predominantly in the C/J region, which, in the case of MYEOV, brings the MYEOV gene under the control of the 3' Eα1 enhancer. In CCND1 translocations by contrast, the Eμ enhancer controls CCND1 expression. MYEOV overexpression is a possible prognostic factor in MM.

[Download] MYEOV/IGH Gene Fusion Probe Instructions

[Download MSDS] MSDS