Cat.# FP-022: 1q21 Gene Amplification Probe Detection Kit
Gain or amplification of chromosome arm 1q21 (1q21+) is the most frequent adverse chromosomal aberration in MM, occurring in 40% of patients at diagnosis. It occurs in a subclone of the tumor as a secondary genomic event and is more amplified as the tumor progresses and a risk factor for the progression from smoldering multiple myeloma to MM. Patients with this unfavorable cytogenetic abnormality are considered to be high risk with a poor response to standard therapies.
[Download] 1q21 Gene Amplification Probe Instructions
[Download MSDS] MSDS