IVD - FP075 TFE3 Gene Break Apart Probe Detection Kit

Cat.# FP-075: TFE3 Gene Break Apart Probe Detection Kit (IVD)

[Overview] 

TFE3 (Transcription Factor Binding To IGHM Enhancer 3) gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. [provided by RefSeq, Aug 2013].

[Download] TFE3 Gene Break Apart Probe Instructions

[Download MSDS] MSDS